Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,171 – 4,185 of 5,343 results

4,171

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000379263 SECO RAPAMYCIN ETHYL 50MG

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4,172

Medchemexpress LLC Glycodeoxycholic acid-d4 | 1069132-37-1 | MFCD06658888 | 99.9% | 453.65 | C26H39D4NO5 | 1MG

Glycodeoxycholic acid-d4 is the deuterium-labeled form of the endogenous bile acid glycodeoxycholic acid, provided as a stable isotope internal standard for quantitative analytical methods such as LC-MS and GC-MS. It is intended for use in metabolomics and bioanalytical assays where isotopically labeled standards are required; storage and solubility instructions are provided to preserve analytical integrity.

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4,173

Medchemexpress LLC Ginsenoside Rh2 | 78214-33-2 | MFCD00800712 | 622.87 | 50 MG

Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. It induces cancer cell apoptosis in a multi-path manner, making it a promising candidate for anti-tumor drug development. Ginsenoside Rh2 triggers p53-dependent Fas expression, leading to caspase-8 activation, and also initiates a p53-independent caspase-9-mediated intrinsic pathway to cause cancer cell death.

Induces activation of caspase-8 and caspase-9.
Induces cancer cell apoptosis through multiple pathways.
Triggers p53-dependent Fas expression.
Activates p53-independent caspase-9-mediated intrinsic pathway.
Demonstrates cytotoxic activity against various human cancer cell lines (HeLa, SK-HEP-1, SW480, PC-3, A549, B16, B16-F10, DU-145, HCT-116, HL-60, HepG2, Huh-7, Jurkat, K562, KG-1, Kasumi 1, LNCaP, MCF7, MDA-MB-231, REH, THP-1, U-937).
Enhances antitumor immunological response in a melanoma mice model.

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4,174

Medchemexpress LLC Remogliflozin etabonate (GSK189075) | 442201-24-3 | 99.64% | 522.59 | 5 MG

Remogliflozin etabonate (GSK189075) is an orally active, selective, and low-affinity sodium glucose cotransporter (SGLT2) inhibitor. It functions as a proagent derived from benzylpyrazole glucoside and is metabolized into its active form, Remogliflozin, within the body. This compound has demonstrated antidiabetic efficacy in rodent models.

Orally active and selective SGLT2 inhibitor
Functions as a proagent of Remogliflozin
Exhibits antidiabetic efficacy in rodent models

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4,175

Medchemexpress LLC Notoginsenoside Fa | 88100-04-3 | MFCD29904542 | 99.0% | 1241.41 | C59H100O27 | 10 MG

Notoginsenoside Fa is a protopanaxadiol (PPD)-type saponin isolated from Panax notoginseng. Supplied as a white to off-white solid for research use, it has been studied for potential neuroprotective activity, including activation and recovery of degenerated brain function.

Purity: 99.0%
Cas number: 88100-04-3
Chemical formula: C59H100O27
Molecular weight: 1241.41
Appearance: white to off-white solid
Intended for research use only; not for human or veterinary use.

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4,176

Medchemexpress LLC Ginsenoside F4 | 181225-33-2 | 5 MG

Ginsenoside F4 (GF4) is a ginseng saponin isolated from notoginseng or red ginseng. It demonstrates an inhibitory effect on human lymphocytoma JK cells by inducing apoptosis. GF4 also inhibits matrix metalloproteinase 13 (MMP 13) expression in IL-1β-treated chondrocytes and blocks cartilage breakdown in rabbit cartilage tissue culture, suggesting its therapeutic potential for preventing cartilage collagen matrix breakdown in diseased tissues.

Isolated from notoginseng or red ginseng
Induces apoptosis in human lymphocytoma JK cells
Inhibits matrix metalloproteinase 13 (MMP 13) expression
Blocks cartilage breakdown in rabbit cartilage tissue culture
Shows therapeutic potential for preventing cartilage collagen matrix breakdown

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4,177

Medchemexpress LLC Prednisolone hemisuccinate | 2920-86-7 | 99.9% | 50 MG

Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, used to treat various inflammatory and auto-immune conditions. It is for research use only and not sold to patients.

Synthetic glucocorticoid
Derivative of cortisol
Used to treat inflammatory and auto-immune conditions

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4,178

Medchemexpress LLC Hydrocortisone-d4 (Cortisol-d4) | 73565-87-4 | 366.48 | 1 MG

Hydrocortisone-d4 is the deuterium labeled Hydrocortisone, a steroid hormone or glucocorticoid secreted by the adrenal cortex. This compound is intended for research use only. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.

Used as a tracer.
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

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4,179

Medchemexpress LLC HY-12316 5mg Medchemexpress, 20(S)-Hydroxycholesterol CAS:516-72-3 Purity:>98%

Medchemexpress, HY-12316 5mg 20(S)-Hydroxycholesterol CAS:516-72-3 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC 50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,180

Medchemexpress LLC HY-15257A 2mg Medchemexpress, Mavoglurant (racemate) CAS:1636881-61-2 Purity:>98%

Medchemexpress, HY-15257A 2mg Mavoglurant (racemate) CAS:1636881-61-2 Mavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,181

Medchemexpress LLC Gypenoside XLIX | 94987-08-3 | 1047.23 | 20 MG

Gypenoside XLIX is a multifunctional bioactive compound isolated from Gynostemma pentaphyllum. It acts as a PPAR-α agonist and binds to SIRT1. It inhibits TLR4-mediated NF-κB signaling pathway activation, reduces ROS accumulation, and alleviates hepatic inflammatory injury. It targets SIRT1 to block YAP-NLRP3 activation, improving sepsis-induced cardiomyopathy. The compound is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis, and chronic inflammation.

Acts as a PPAR-α agonist
Inhibits TLR4-mediated NF-κB signaling pathway
Reduces ROS accumulation
Alleviates hepatic inflammatory injury
Targets SIRT1 to block YAP-NLRP3 activation
Prevents acute kidney injury

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4,182

Medchemexpress LLC Ercalcidiol-d3 (25-Hydroxy Vitamin D2-d3) | 1217467-39-4 | 99.9% | 415.67 | 500 UG

Ercalcidiol-d3 is the deuterium labeled Ercalcidiol, a metabolite of Vitamin D2. It can be used as an indicator of vitamin D status. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.

Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

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4,183

Medchemexpress LLC Ginsenoside Rk2 | 364779-14-6 | 1 MG

Ginsenoside Rk2 is a dammarane glycoside isolated from processed ginseng. Intended for research use only, it has 99.25% purity and appears as an off-white to light yellow solid.

Molecular weight: 604.86
Formula: C36H60O7
Source: Panax ginseng C. A. Meyer (Araliaceae plants)
Storage: -20°C, protected from light. In solvent, -80°C for 6 months or -20°C for 1 month.
In vitro solubility: Soluble in DMSO (50 mg/mL, 82.66 mM), requires sonication.
In vivo solubility: Protocols for suspended (1.25 mg/mL in DMSO/PEG300/Tween-80/Saline) or clear solution (≥ 1.25 mg/mL in DMSO/Corn Oil).
Cellular effect: IC50 > 10 μM against human A549, HL-60, MCF7, and SW480 cells.
Classifications: Natural products, terpenoids, triterpenes, inflammation/immunology.

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4,184

Medchemexpress LLC Gypenoside L | 94987-09-4 | 5 MG

Gypenoside L is a saponin found in Gynostemma pentaphyllum. It increases SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines, and activates p38, ERK MAPK, and NF-κB pathways to induce senescence. It also exhibits anti-tumor and anti-inflammatory activities.

Saponin derived from Gynostemma pentaphyllum
Increases SA-β-galactosidase activity
Promotes production of senescence-associated secretory cytokines
Activates p38 and ERK MAPK pathways
Activates NF-κB pathway
Induces senescence
Exhibits anti-tumor activity
Exhibits anti-inflammatory activity

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4,185

Medchemexpress LLC Alisol B | 18649-93-9 | 472.70 | 1 MG

Alisol B is a triterpene that exhibits diverse biological activities, making it valuable for various research applications. It is known to bind human soluble epoxide hydrolase (sEH) and reduce its activity. This compound also plays a role in inhibiting RANKL-induced JNK phosphorylation, osteoclast formation, and SERCA pump activity, while promoting calcium mobilization and autophagy. Alisol B can be used for research into conditions such as hypercalcemia, osteoporosis, rheumatoid arthritis, acute kidney injury, and breast cancer.

Inhibits sEH activity
Reduces osteoclast formation
Induces calcium mobilization
Activates CaMKK-AMPK-mTOR pathway
Promotes autophagic flux and autophagosome formation
Induces G1 phase cell cycle arrest
Activates endoplasmic reticulum stress and unfolded protein responses
Induces cancer cell apoptosis

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Alcohols and polyols

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Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Glycodeoxycholic acid-d4 | 1069132-37-1 | MFCD06658888 | 99.9% | 453.65 | C26H39D4NO5 | 1MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ginsenoside Rh2 | 78214-33-2 | MFCD00800712 | 622.87 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Remogliflozin etabonate (GSK189075) | 442201-24-3 | 99.64% | 522.59 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Notoginsenoside Fa | 88100-04-3 | MFCD29904542 | 99.0% | 1241.41 | C59H100O27 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ginsenoside F4 | 181225-33-2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Prednisolone hemisuccinate | 2920-86-7 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hydrocortisone-d4 (Cortisol-d4) | 73565-87-4 | 366.48 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-12316 5mg Medchemexpress, 20(S)-Hydroxycholesterol CAS:516-72-3 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-15257A 2mg Medchemexpress, Mavoglurant (racemate) CAS:1636881-61-2 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gypenoside XLIX | 94987-08-3 | 1047.23 | 20 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ercalcidiol-d3 (25-Hydroxy Vitamin D2-d3) | 1217467-39-4 | 99.9% | 415.67 | 500 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ginsenoside Rk2 | 364779-14-6 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gypenoside L | 94987-09-4 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alisol B | 18649-93-9 | 472.70 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More